Power Tools for Technical Communication:
Headings, CSS, and Web Pages

In this lab, you rework the tagging for a web page using Cascading Style Sheets (CSS). See chapter 7 Power Tools for Technical Communication for details on creating CSS. To be ready for this project, you also need to have have studied Chapter 17 and have done at least one other web-page formatting project:
  1. Using a simple text editor or web-page editor of your choice, create a simple web page like the one shown in Chapter 17 entitled My First Web Page. Between the <TITLE> and </TITLE> tags and between the <H1> and </H1> tags, substitute Headings & CSS Practice.
  2. Copy the following unformatted text, and paste it into the web page you just started.
  3. Create the CSS definitions within the HEAD tags at the top of the page as follows: an H2 that is centered and uses the brownish (#800000) Arial font; a second-level heading that uses a bold brownish (#800000) Arial font; and a third-level heading that uses uses a bold brownish (#800000) font (but not Arial).
  4. Take out all that complicated tagging (highlighted in red below) with each of the headings in the text and replace it with your CSS tags.
  5. Make sure that this page looks just as it did with the original tagging.
  6. Put your name, Headings & CSS Practice 1, and the date on this document, and print it out for your instructor.
  7. And finally, move the CSS definitions to a separate .css file and set a link to that file. (This will demonstrate how you can use CSS for multiple web pages.)
  8. Make sure that this version of the page looks just as it did with the original tagging.
  9. Put your name, Headings & CSS Practice 2, and the date on this document, and print it out for your instructor.

<FONT FACE="Arial" COLOR="#800000"><CENTER><H2>Recommendation Report: COX-2 Inhibitors</H2></CENTER></FONT>

People suffering from the joint pain, stiffness and inflammation associated with arthritis are typically interested in available drugs to relieve this unpleasant side effect of the disease. Arthritis sufferers whether they have osteoarthritis (OA), rheumatoid arthritis (RA), lupus or one of the other 100 plus forms of the disease are afflicted to some degree with joint pain and stiffness caused by the condition. One class of drugs used by physicians to treat arthritis joint pain and inflammation is called NSAIDS (non-steroidal anti-inflammatory drugs), and within this class is a sub-class known as COX-2 Inhibitors. Currently, only two drugs are available within the COX-2 inhibitor sub-class, Celebrex and Vioxx. This recommendation report is limited to these two COX-2 inhibitor drugs. Celebrex and Vioxx work in similar ways, but each has its unique characteristics as well. These drugs will be evaluated based on cost, recommended dosage, and frequency of ulcers in patients.

<FONT FACE="Arial" COLOR="#800000"><B>Development Background</B></FONT>

"Despite all of the new options for treating arthritis in recent years, NSAIDS are still by far the most prescribed and most widely used medications for arthritis," according to Mary Anne Dunkin with <I>Arthritis Today</I> [1:42]. All NSAIDS work by blocking the production of body chemicals known as prostaglandins. By doing this, NSAIDS reduce inflammation and relieve joint pain and stiffness. According to <I>Arthritis Today</I>, "Unfortunately, blocking prostaglandins also has some adverse effects in some people, including stomach ulcers and increased bleeding" [1:42].

Two enzymes called COX-1 and COX-2 are present in the human body. COX-1 helps regulate normal cell function in the stomach. COX-2 "plays a role in causing arthritis pain and inflammation" [2]. COX-2 inhibitors were created to provide the same level of relief for joint pain and inflammation as other NSAIDS. However, these drugs work without affecting the way the body naturally protects the stomach. COX-2 inhibitors attack only the inflammation-causing prostaglandins (COX-2 enzymes) without damaging the stomach-protecting prostaglandins (COX-1 enzymes). Consequently, prescriptions for this class of drugs have increased significantly in the past few years.

<B>Note:</B> At least two new COX-2 inhibitors are currently in clinical testing for RA and OA. These drugs should have greater inflammation-reducing abilities with even fewer side effects on the stomach than the drugs reviewed in this recommendation report [1:44].

<FONT FACE="Arial" COLOR="#800000"><B>Requirements for evaluation</B></FONT>

Currently, only two drugs are classified as COX-2 inhibitors, Celebrex and Vioxx. Both of these drugs provide relief for arthritis pain, inflammation and stiffness helping patients with their daily activities, like walking, standing or climbing stairs. These drugs also provide relief while an arthritis sufferer is sitting or lying in bed. Although many drugs can be classified as NSAIDS, both prescription and non-prescription, only Celebrex and Vioxx are COX-2 inhibitors. This recommendation report will focus exclusively on COX-2 inhibitor drugs since these drugs are the only ones currently available that provide protection for an arthritis patient's stomach while also relieving joint pain, stiffness and inflammation. The following points of comparison will be made for Celebrex and Vioxx:

<LI>Cost for a 30-day supply
<LI>Manufacturer's dosage recommendations
<LI>Frequency of ulcers in patients during clinical trials

<FONT FACE="Arial" COLOR="#800000"><B>Comparison of Celebrex and Vioxx</B></FONT>

The three areas of comparison for these two COX-2 inhibitor drugs will be (1) cost, (2) recommended dosage and (3) ulcer frequency.

<B><FONT COLOR="#800000">Cost.</FONT></B> Since many prescription-drug insurance plans cover the cost of a month's supply, price comparisons are based on a 30-day supply. Costs can vary somewhat from one pharmacy to another, and patients can reduce their drug cost by using mail-order suppliers or other such methods of purchasing prescriptions. However, for this comparison only one pharmacy was selected to illustrate how the cost of Celebrex and Vioxx compare. Also, note that these two drugs are produced in different size doses. Celebrex comes in 100-400 milligram (mg) tablets and Vioxx comes in 25-50 milligram (mg) tablets as well as a liquid form. For this cost comparison, 200 mg Celebrex and 25-mg Vioxx tablets were selected, because these dosages are comparable in effectiveness for treating OA or RA pain [1:44].

Information and programs provided by hcexres@prismnet.com.